9.9. ROCHE AND SPARK THERAPEUTICS DISCLAIM ANY INTENT OR OBLIGATION TO UPDATE ANY FORWARD-LOOKING STATEMENTS AS A RESULT OF DEVELOPMENTS OCCURRING AFTER THE PERIOD COVERED BY THIS REPORT OR OTHERWISE. It is mandatory to procure user consent prior to running these cookies on your website. Search job openings, see if they fit - company salaries, reviews, and more posted by Spark Therapeutics employees. Associated People Federico Mingozzi Spark Therapeutics, Inc. is hiring for a Scientist Immunology in Philadelphia, PA . Philadelphia, Pennsylvania, United States - Part of a team testing the immunogenicity of AAV-based gene . He is also the at-large director on the American Society of Gene and Cell Therapy (ASGCT) board of directors. Spark Therapeutics is hiring a Research Immunology Lead, with an estimated salary of $100,000 - $150,000. We also use third-party cookies that help us analyze and understand how you use this website. Pre-clinical Immunology Lead On December 19, 2017, the FDA approved a novel gene therapy that treats diseases that affect vision. As CTO, Cynthia oversees pipeline process development, preclinical and clinical manufacturing and the commercial manufacturing and distribution of LUXTURNA (voretigene neparvovec-rzyl). At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. Phone: 1-855-SPARKTX / +1 215-220-9300. She spent more than 18 years at Pfizer in a variety of roles including portfolio and project management, logistics and supply chain, pharmaceutical sciences and as a scientist in medicinal chemistry. Leadership truly cares about employee engagement and workplace satisfaction. This ecosystem will ultimately benefit students through co-ops and career opportunities, benefit faculty through collaborative research and training, and benefit the surrounding community through the creation of a pipeline to employment. As a member of larger Immunology Team in the Translational Department, the Preclinical Immunology Lead is responsible for strategic planning . Prior to joining Bain in 2010, Michael was a partner at Monitor Group and head of the New York office, where he supported pharmaceutical treatment launches and growth strategies for 10 years. Find out more about how we strive to turn genes into medicines for patients with inherited diseases, including inherited retinal diseases (IRDs), liver-directed diseases such as hemophilia, and neurodegenerative diseases. . Spark is a member of the Roche Group. Through a 99-year ground lease of Drexel Universitys F Lot, the new center will be located at the intersection of 30th and Chestnut Streets and will create opportunities for collaboration with Drexel University and Philadelphias booming life sciences community. These cookies will be stored in your browser only with your consent. She eventually returned to Genentech, taking responsibility for the global clinical development program for HEMLIBRA during which time she led the transition from Phase 1 through to global registration for adults and children with hemophilia A. Gallia is board-certified in hematology and earned an M.D. These cookies do not store any personal information. Overall, a great medium sized pharm company with a noble mission. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. Prior to her role at Honeywell, she was the Executive Vice President, Technical Development, Operations and Supply Chain for Actinium Pharmaceuticals, Inc. Cynthia also worked at Ipsen Biosciences, the U.S. subsidiary of Ipsen, serving as President and, prior to that, Vice President of Technical Operations and Development. Jennifer and her team are responsible for translating business priorities into talent, communication and engagement strategies that strengthen Sparks competitiveness and ability to fulfill its mission to challenge the inevitability of genetic disease. You also have the option to opt-out of these cookies. Philadelphia, PA 19104 She serves as the principal physician and resident medical expert at Spark. Its pipeline includes a product candidate targeting choroideremia (CHM), which is in a Phase I/II clinical . These cookies do not store any personal information. The closing of the transaction is expected to take place in the second quarter of 2019. To further aid in attraction and retention, starting in 2022, we will offer expanded mental health resources and extend benefits to part-time employees. as a member of larger immunology team in the translational department, the preclinical immunology lead is responsible for strategic planning, execution, and reporting of pre-clinical immunology studies; initiates and directs immunological initiatives to support all spark therapeutic areas with the goal of increasing safety and efficacy of all "Filtering down to just Philadelphia proper does reveal that . He is also the at-large director on the American Society of Gene and Cell Therapy (ASGCT) board of directors. For more information, please visitwww.roche.com. This website uses cookies and similar technologies to optimize and improve the experience on our site (. There, he spearheaded the development ofin vivogene therapies for inherited diseases. Federico was involved in several first-in-human clinical studies of gene therapy based on the AAV vector platform while serving as the director of translational research the Center for Cellular and Molecular Therapeutics, at CHOP. Apply to Bioanalytical Study Lead, Administrative Assistant, Laboratory Technician and more! In particular, Sparks hemophilia A program could become a new therapeutic option for people living with this disease. These cookies will be stored in your browser only with your consent. Gallia first joined Genentech in 2009, where she worked in both early and late-stage clinical development. Drexel raised funds to build a facility to house a state-of-the-art public elementary school and a middle school on the site that will also be the location of a 450,000-square-foot Health Sciences Building where the College of Nursing and Health Professions and the College of Medicine will be co-relocated from other locations in the city. Our mission at Spark Therapeutics is to challenge the inevitability of genetic disease by discovering, developing and delivering potential treatments in ways unimaginableuntil now. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. Ron previously served as Chief Operating Officer, where he was responsible for leading product strategy development and execution for Sparks early and late-stage pipeline assets, including the governance and proactive management necessary to bring more gene therapies to patients living with genetic diseases. This Life Sciences job in Science & Education is in Philadelphia, PA 19102. Spark Therapeutics is hiring a Scientist Immunology, with an estimated salary of $80,000 - $100,000. We are glad to share with you an update on the status of the Pompe clinical development program at Spark Therapeutics. Working at Spark Therapeutics. September 25, 2017 Dr. Federico Mingozzi is the chief scientific officer at Spark Therapeutics, bringing two decades of experience in gene therapy, immunology, as well as biochemistry and molecular biology in both industry and academic settings. This Life Sciences job in Science & Education is in Philadelphia, PA 19102. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the worlds largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. About Spark Therapeutics. Meet the Spark corporate management team About Compliance and Ethics Industry recognitions This website uses cookies and similar technologies to optimize and improve the experience on our site (, Return to Corporate Social Responsibility. More than thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Spark Therapeutics, Inc. is a gene therapy company. Centerview Partners is acting as financial advisor to Spark Therapeutics and Goodwin Procter LLP is acting as legal counsel to Spark Therapeutics. Spark Therapeutics is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies. About Spark Therapeutics . THE SOLICITATION AND OFFER TO BUY SPARK THERAPEUTICS COMMON STOCK WILL ONLY BE MADE PURSUANT TO AN OFFER TO PURCHASE AND RELATED MATERIALS. Scientist (Current Employee) - Philadelphia, PA - June 11, 2021. Specialties: AA-mediated gene therapy immunology, Biologics (large molecules). As Spark Therapeutics Chief Executive Officer, Ron Philip leads a team of talented individuals working together to develop new therapies for people living with genetic diseases. from the University of California, Berkeley. Spark Therapeutics Profile and History . Drexel is rethinking its institutional boundaries and creating a vibrant presence and ecosystem of innovation in and around University City while delivering on the Universitys public purpose as an anchor institution for Philadelphia. View all jobs at Spark Therapeutics Report Job. Generally, has 6 years of relevant post-graduate experience in biotech or biopharma. Philadelphia, PA 19104 4.4/5 on G2 Crowd. Spark Therapeutics to Invest $575M in New 500k Square Foot State-of-the-Art Gene Therap.. Since the initial evidence that AAV vectors can elicit capsid T cell responses in humans, which can affect the duration . You also have the option to opt-out of these cookies. Previous personnel management. Dr. Gallia Levy is the Chief Medical Officer at Spark Therapeutics and leads strategic and operational teams throughout the product development lifecycle with responsibility for setting the global development strategy for current and pipeline programs. 40% Detractors. At Spark, we see the path to a world where no life is limited by genetic disease. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. This website uses cookies and similar technologies to optimize and improve the experience on our site (. We are proud to partner with Spark Therapeutics in advancing life sciences research and innovation in University City, said John Fry, president, Drexel University. We also use third-party cookies that help us analyze and understand how you use this website. Roche has signed a definitive merger agreement to acquire all outstanding shares of US-based gene therapy company Spark Therapeutics for $114.50 per share, corresponding to a total of around $4.8bn on a fully diluted basis.. in Molecular and Cellular Biology from the University of Paris, VI and she holds a B.A. His work continued to focus on the characterization of human immune responses to AAV vectors and on the development of strategies to overcome immune responses in gene transfer. Following completion of the tender offer, Roche will acquire all remaining shares at the same price of $114.50 per share through a second step merger. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now. Roche is the world's largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Spark Therapeutics employees in different jobs earn different salaries. She served as Vice President of HR for Teva Pharmaceuticals, leading the HR function for its U.S. business, and at Shire Pharmaceuticals (now part of Takeda), as the Chief of Staff to the CHRO, in addition to a number of senior-level HR Business Partner roles. A best place to work headquartered in Philadelphia, Spark is fueled by a diverse, experienced team united in a collective goal: challenging the inevitability of genetic diseases. Beyond his work at Spark, Paul plays an active role within community and cultural organizations, serving on the Boards of Directors for the Wharton Esherick Museum and the Jane Austen Society of North America. People who searched for Spark Therapeutics jobs also searched for therapeutic mentor, board certified behavior analyst, behavioural therapist, board certified behaviour analyst, aba therapist.If you're getting few results, try a more general search term. Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve peoples lives. For more information, please visit www.roche.com. Spark Therapeutics chief executive officer Jeffrey D. Marrazzo said: "We had a strong second quarter, starting with the shipment of 12 vials of Luxturna (voretigene neparvovec-rzyl), as well as the work that went into the completion in early July of the transition to Pfizer and Phase 3 initiation of SPK-9001 for haemophilia B, now known as fidanacogene elaparvovec. Terms of the Agreement This partnership will generate unparalleled opportunities for our students and faculty to participate in groundbreaking research and to help create and sustain the workforce that will make West Philadelphia a leader in the life sciences revolution., Since founding Spark, we knew Philadelphia had the potential to be the life sciences hub it is becoming today, added Marrazzo. Federico received his bachelors degree in biology and his Ph.D. in biochemistry and molecular biology from the University of Ferrara in Italy, and his M.B.A. from Drexel University. THE OFFER TO PURCHASE, SOLICITATION/RECOMMENDATION STATEMENT AND RELATED MATERIALS WILL BE FILED WITH THE SEC, AND INVESTORS AND SECURITY HOLDERS MAY OBTAIN A FREE COPY OF THESE MATERIALS (WHEN AVAILABLE) AND OTHER DOCUMENTS FILED BY ROCHE AND SPARK THERAPEUTICS WITH THE SEC AT THE WEBSITE MAINTAINED BY THE SEC AT WWW.SEC.GOV. His experience spans multiple therapeutic areas, including rare disease, the central nervous system and ophthalmology across a wide range of modalities. Neutralizing antibodies to adeno-associated virus (AAV) vectors are highly prevalent in humans 1,2, and block liver transduction 3-5 and vector readministration 6; thus, they represent a major limitation to in vivo gene therapy.Strategies aimed at overcoming anti-AAV antibodies are being studied 7, which often involve immunosuppression and are not efficient in removing pre-existing antibodies. Spark is a member of the Roche Group. and Ph.D. in Molecular and Cellular Biology from the University of Michigan, during which time discovered ADAMTS13, responsible for Thrombotic Thrombocytopenic Purpura (TTP). Spark Therapeutics is hiring a Senior Scientist - Immunology, with an estimated salary of $80,000 - $100,000. 40% Promoters. 3737 Market Street IMPORTANT ADDITIONAL INFORMATION AND WHERE TO FIND IT Philadelphia, PA 19104 He then joined the French National Institute of Health and Medical Research (INSERM) as Research Director and Genethon, a leading French nonprofit R&D organization focused on gene therapy for rare diseases, as Team Leader. Join us on a journey through uncharted territory - seeking to bring gene therapy for genetic diseases to people worldwide. The development, growth, and career advancement of our workforce is a top . INVESTORS AND SECURITY HOLDERS MAY ALSO OBTAIN FREE COPIES OF THE SOLICITATION/RECOMMENDATION STATEMENT AND OTHER DOCUMENTS FILED WITH THE SEC BY SPARK THERAPEUTICS AT www.sparktx.com. Roche affirms its long-term commitment to Philadelphia as gene therapy center of excellence, Spark signs 99-year ground lease of Drexel Universitys property, to create a premier environment for development of next generation of life sciences talent. From our prestigious universities and hospitals, to the investments poured annually into scientific research and the sheer volume of medical professionals that receive training here, Philadelphia has every ingredient necessary for life sciences companies to succeed. He also was responsible for the other functions, including commercial development, marketing, pricing and reimbursement, government affairs, program and alliance management, commercial operations, diagnostics, market access and patient services functions. State-of-the-art, in-house expertise in vector manufacturing, Innovative scientific and regulatory strategies, Strong commitment to improve patient care, This website uses cookies and similar technologies to optimize and improve the experience on our site (. 59 Spark Therapeutics Spark jobs. Niki Gianakaris This Life Sciences job in Science & Education is in Philadelphia, PA 19102. Moreover, for the eleventh consecutive year, Roche has been recognised as one of the most sustainable companies in the Pharmaceuticals Industry by the Dow Jones Sustainability Indices (DJSI). Since joining Spark in 2017, he has played a key role in Sparks rapid growth and achievements most notably, directing the commercial launch of Sparks first approved gene therapy, LUXTURNA (voretigene neparvovec-rzyl). But opting out of some of these cookies may have an effect on your browsing experience. Cowen also acted as a financial advisor in this transaction to Spark Therapeutics. She later moved to Portola Pharmaceuticals, where she led the clinical development program for hematology and oncology indications spanning Phases 1 to registrational trials. Join the world's top companies using Zoominfo. This helps ensure that Spark meets the needs of its employees while further positioning us as an employer of choice. as a member of larger immunology team in the translational department, the preclinical immunology lead is responsible for strategic planning, execution, and reporting of pre-clinical immunology studies; initiates and directs immunological initiatives to support all spark therapeutic areas with the goal of increasing safety and efficacy of all You also have the option to opt-out of these cookies. Necessary cookies are absolutely essential for the website to function properly. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare a strategy that aims to fit the right treatment to each patient in the best way possible. We are also excited to continue the investments in Sparks broad product portfolio and commitment to Philadelphia as a center of excellence.. He oversees Sparks Legal and Compliance departments, which he has significantly contributed to building and developing during his nearly six-year tenure with the company. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. Spark Therapeutics pays an average salary of $89,814 per year, or $43.18 an hour. The closing of the tender offer will be subject to a majority of Spark Therapeutics outstanding shares being tendered. Healthcare. These cookies do not store any personal information. In addition, the transaction is subject to the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 and other customary conditions. Michael joins Spark Therapeutics from Bain & Company, where he served as a partner in the healthcare practice for a decade. She also spent time at the Pasteur Institute during which she received an M.S. The organisation is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies for genetic diseases, including inherited retinal disorders, haemophilia, lysosomal storage disorders and neurodegenerative diseases. philadelphia, feb. 25, 2019 (globe newswire) spark therapeutics (nasdaq: once), a fully integrated, commercial gene therapy company dedicated to challenging the inevitability of genetic disease, announced today that it has entered into a definitive merger agreement for roche to fully acquire spark therapeutics at a price of $114.50 per share in At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. 20% Passives. Paul holds a BSFS from Georgetown Universitys School of Foreign Service, an M.B.A. from the Kellogg School of Management at Northwestern University, and a JD from Washington and Lee University School of Law. The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2018 employed about 94,000 people worldwide. . We also use third-party cookies that help us analyze and understand how you use this website. In this role, Michael focused on corporate and business unit strategies, organizational transformations, product launches, growth strategies and new market entries. Jennifer holds a B.S. Our mission Challenge the inevitability of genetic disease by discovering, developing and delivering treatments in ways unimaginable - until now. Select a reason for reporting this job. This website uses cookies to improve your experience while you navigate through the website. cell-based assay development, pre- and non-clinical safety assessment, Drug discovery, Vaccines, immune modulation,. Spark Therapeutics. He then joined the French National Institute of Health and Medical Research (INSERM) as Research Director and Genethon, a leading French nonprofit R&D organization focused on gene therapy for rare diseases, as Team Leader. Spark Therapeutics to Invest $575M in New 500k Square Foot State-of-the-Art Gene Therapy Innovation Center on Drexel's University City Campus Spark Therapeutics, Inc. December 17, 2021,. It is also responsible for the proof-of-concept studies design and execution for treatment of autoimmune diseases, choice of autoimmune indications and establishing the candidate . These cookies will be stored in your browser only with your consent. Prior to joining Spark, Paul served in the U.S. and European legal groups at Merck & Co., Inc. and in the regulatory and legal organizations at Bristol-Myers Squibb where he was Senior Vice President and Deputy General Counsel for the Global Commercialization, Research & Development and Europe groups. There, he spearheaded the development ofin vivogene therapies for inherited diseases. This Allied Health Professionals job in Healthcare is in Philadelphia, PA 19102. To support this mission, Jennifers team is focused on building a strong, values-driven culture, where everyone is respected, feels a sense of belonging and can thrive, and communicating with all of Sparks key stakeholders, including the broader community, to enable meaningful engagement with the Company.

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