The acquisition further reinforces AbbVie's neurology pipeline, as four years ago, Syndesi Therapeutics gained the rights to UCB's. Latest news. The biotech notes that disruption of the synaptic connectivity is found in Alzheimers and other types of dementia. They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. Syndesi Therapeutics Company Profile - Craft As hospitals face consolidation and CIOs are asked to increase staff productivity, tech companies that can support automation with solutions that are easy to onboard are getting heightened interest. Follow @abbvie on Twitter, Facebook, Instagram, YouTubeand LinkedIn. Syndesi Therapeutics SA Information | Syndesi Therapeutics SA Profile AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Share. Join our mailing list. On March 1, 2022 AbbVie (NYSE: ABBV) reported it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio (Press release, AbbVie, MAR 1, 2022, View Source [SID1234609248]). 3D Printing in Healthcare Market Size, Share, Trends Analysis Report By Region, Component (Hardware, Materials, Digital Marketing Trends in Colorectal Cancer. The product, which came to AbbVie in the 2020 Allergan acquisition, is approved for a range of therapeutic indications that include treating muscle spasticity from a stroke or other injury, as well as preventing migraine headaches. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Cognitive impairment observed in various neuropsychiatric and neurodegenerative ailments is claimed to be triggered by synaptic dysfunction. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Syndesi therapeutics - Email Address & Phone Number - Lusha Four years after spinning out from Belgium's UCB, Syndesi Therapeutics and its SV2A modulator programme has been bought by AbbVie for $130 million upfront. It also presents a list of recommendations for addressing these challenges. Syndesi's Series A financing was co-led by Novo Holdings together with Fountain Healthcare Partners, with participation from Johnson & Johnson Innovation JJDC, Inc., SRIW (Socit Rgionale d'Investissement de Wallonie), V-Bio Ventures and Vives Fund, along with UCB Ventures. AbbVie has bolstered its neuropsychiatric and neurodegenerative portfolio with the acquisition of Belgium-based Syndesi Therapeutics in a deal valued at up to $1 billion. Syndesi Therapeutics CEO and key executive team | Craft.co Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. The total value of the deal could. Milestone payments could bring shareholders of the biotech up to $870 million more. Syndesi Therapeutics is a Pharmaceutical Company located in Belgium, Europe, and was founded in 2018. About Bone Therapeutics . In the life science sector, SRIW is investor in more than 30 companies such as I.B.A., Celyad, or Ogeda of which it recently exited. . There is a major unmet need for new therapies that can . With more than 7500 people in approximately 40 countries, the company generated revenue of 4.2 billion in 2016. VIVES II is funded by a dozen leading Belgian and European investors such as the EUROPEAN INVESTMENT FUND (EIF), SFPI-FPIM, BNP PARIBAS FORTIS PRIVATE EQUITY BELGIUM, BPI FRANCE (France), ING BELGIUM, SOFINA, AXA BELGIUM, BELFIUS, IRD (France), NIVELINVEST, REGION BRUXELLES CAPITAL and by SOPARTEC. All rights reserved. Under the deal, AbbVie also gained access to TeneoOne drug, TNB-383B, indicated to treat relapsed or refractory multiple myeloma. Aristea Therapeutics Announces Dosing of First Patient in Phase 2a Trial of RIST4721 in Hidradenitis Suppurativa; August 26 2022 | News No Myth: CEO of ADC upstart calls it quits; Bristol Myers vet Jon Wigginton scales new heights at Bright Peak; August 24 2022 | News Appointments and advancements for Aug. 24, 2022; August 24 2022 | Press Releases AbbVie will pay Syndesi's shareholders a $130 million upfront payment with the potential for Syndesi's shareholders to receive additional contingent payments of up to $870 million based on the achievement of certain predetermined milestones. Regulating the synaptic transmission is a promising approach to treat Alzheimer's disease and other disorders with cognitive impairment. AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio. According to the deal, shareholders of Syndesi will receive an upfront payment of $130m from AbbVie. Back to companies Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. The company is rooted in the groundbreaking research of the VIB laboratory of Ludo Van Den Bosch and in the collaboration between the VIB labs of Joris de Wit and Bart De Strooper. SIRP-DIRECTED ANTIBODIES IN DEVELOPMENT Our novel monoclonal antibodies are designed to change the lives of patients with immunological diseases and cancer. var addy45869 = 'info' + '@'; ABOUT US | Prilenia Therapeutics Driven by science. Curve Therapeutics - Curve Therapeutics Syndesi Therapeutics | CipherBio Syndesi Therapeutics - PMLiVE Syndesi, which is based in Belgium, aims to treat brain disorders by reducing the symptoms of cognitive impairment. Bone Therapeutics has a broad portfolio of innovative allogeneic cell therapy solutions across a range of indications. Syndesi Therapeutics | Sopartec Sirona's current pipeline includes further cosmetic related products for cell preservation and repair, keloid therapy, scar therapy, anti-aging, anti-wrinkle, and . Home - Augustine CAREERS. This investment group formed Syndesi in 2017; the startup licensed SDI-118 from UCB in 2018. In June last year, AbbVie exercised an exclusive option for the acquisition of TeneoOne, a Teneobiosubsidiary. Synaptic dysfunction is believed to underlie the cognitive impairment seen in multiple neuropsychiatric and neurodegenerative disorders. Syndesi will build on a rich legacy of work by UCB to further develop these novel SV2A modulators to investigate their potential to improve cognition in diseases such as Alzheimers Disease, other dementias and cognitive impairment associated with schizophrenia. Syndesi Therapeutics | Drug Developments | Pipeline Prospector Connecting Health Systems and Life Science Researchers To Maximize the Potential of Real-world Evidence. Syndesi Therapeutics Archives - pharmaphorum Syndesi Therapeutics is developing molecules which act in a unique way on the synaptic vesicle protein SV2A. Important factors that could result in such differences include: changes in general economic, business and competitive conditions, the inability to obtain necessary regulatory approvals or to obtain them on acceptable terms, costs associated with research and development, changes in the prospects for products in the pipeline or under development by UCB, effects of future judicial decisions or governmental investigations, product liability claims, challenges to patent protection for products or product candidates, changes in laws or regulations, exchange rate fluctuations, changes or uncertainties in tax laws or the administration of such laws and hiring and retention of its employees. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience Portfolio Syndesi Therapeutics - Pharmaceutical Company, Belgium - SWFI Approach | UCB Ventures Syndesi Therapeutics SA, a clinical stage biotechnology company developing novel modulators of the synaptic vesicle protein SV2A for the treatment of cognitive impairment, announces results from two Phase I studies of its lead compound SDI-118, supporting further development of this promising molecule. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Its current portfolio fair value is above 150 million . The company has also benefited from support from the Walloon Region. You are at any time able to change your cookie preferences via the cookie settings on the website. Four years after spinning out from Belgium's UCB, Syndesi Therapeutics and its SV2A modulator programme has been bought. Discover our pipeline Founded in 2019, Augustine Therapeutics is a biotech company in Leuven, Belgium. Presently in Phase Ib clinical trials, SDI-118 is being analysed for its potential ability to boost synaptic efficiency by acting on nerve terminals. For more information about AbbVie, please visit us atwww.abbvie.com. Syndesi has an exclusive, worldwide license from UCB to develop and commercialise a series of novel, pro-cognitive SV2A modulators. . Our News | UCB Ventures Also, UCB or others could discover safety, side effects or manufacturing problems with its products after they are marketed. They are also entitled to get further contingent payments of up to $870m on meeting specific pre-set milestones. The objective of the fund is to invest in the development of start-ups, from validation of the technology to commercial maturity. UCBs Neuroscience researchers in Belgium have designed a unique class of novel SV2A modulators. Company Presentation . Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. In addition to being the major shareholder in the Novo Group companies, Novo Holdings provides seed and venture capital to development-stage companies, takes significant ownership positions in well-established companies within the life sciences and manages a broad portfolio of financial assets. Contact Email info@syndesitherapeutics.com Phone Number +32 10 280 238 Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). Is AbbVie Stock a Buy Now? | The Motley Fool All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including estimates of revenues, operating margins, capital expenditures, cash, other financial information, expected legal, political, regulatory or clinical results and other such estimates and results. The mechanism is currently being evaluated . Anthos Therapeutics is a clinical-stage biopharmaceutical company focused on the development and commercialization of genetically and pharmacologically validated innovative therapies to advance care for people living with cardiovascular and metabolic (CVM) diseases. Syndesi Acquired by Abbvie for up to $1 Billion Read More Our Science The pharmaceutical industry's most comprehensive news and information delivered every month. . AbbVies neuroscience drug prospects are from its partnership with Calico Life Sciences, a firm founded by Google parent company Alphabet. We are excited to see Syndesi develop our novel pro-cognitive SV2A modulators to create value for patients with cognitive impairment, said Dhavalkumar Patel, UCBs Chief Scientific Officer and Executive Vice President. Syndesi Therapeutics is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. Novo Holdings is a private limited liability company wholly owned by the Novo Nordisk Foundation. Milestone payments could bring shareholders of the biotech up to $870. AbbVie announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. Though the deal, AbbVie will gain access to Syndesis portfolio of SV2A modulators. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Syndesi Therapeutics - Funding, Financials, Valuation & Investors document.getElementById('cloak45869').innerHTML = ''; With an upfront payment of $130 million, AbbVie gains Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Unlike, UCB is the world leader in SV2A research, having discovered and developed two major anti-epileptic drugs treating patients around the world. "We have been impressed with the vision of AbbVie's neuroscience R&D team, who share our view on the therapeutic potential of SDI-118 in a range of neurologic diseases," said Jonathan Savidge, chief executive officer, Syndesi Therapeutics. Syndesi Therapeutics is building upon a rich legacy of research on SV2A conducted at UCB. Products or potential products which are the subject of partnerships, joint ventures or licensing collaborations may be subject to differences between the partners. +972 77 555 8482 +31 35 808 0509 About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Syndesi Therapeutics is developing molecules that uniquely modulate the synaptic vesicle protein SV2A, which plays a central role in synaptic transmission (the communication between neurons in the brain). The companys drugs are small molecules that modulate synaptic transmission, which is the communication that happens between neurons in the brain. WHO WE ARE . UCB and investor syndicate led by Novo Seeds launch Syndesi Syndesi benefits both from UCBs research expertise and from an impressive syndicate of experienced investors and their respective networks., Cognitive impairment remains an area of significant unmet need for patients not only with Alzheimers Disease but also more broadly across a range of neurological disorders, and we are excited about the potential promise of this novel therapeutic approach, says Morten Graugaard Dssing, Principal at Novo Seeds. You need JavaScript enabled to view it. IMPROVING THE LIVES OF PATIENTS AND THEIR FAMILIES. Do not sell my information, Bain Capital-Backed Emalex Bio Lands $250M for Pivotal Test of Tourette Drug, How To Create Digital Health Apps That Serve as Useful Tools (Not Unnecessary Work), Why Digital Health Collaborations Are the Future of Medtech, Rubiuss New Cell Therapy Strategy Runs Out of Time & Money; Workforce Is Cut by 82%, Startup Founded by Brown Undergrads Raises $14M to Improve Care for Vulnerable Seniors, AMA: CMS 2023 Physician Fee Schedule Would Create Financial Instability, Carta Healthcare Rakes in $20M with Hopes of Selling its Tech to More Hospitals, CVS, Walgreens Will Pay $10 Billion Total To Settle Opioid-Related Lawsuits. Other executives include John Kemp, Chief Scientific Officer; Torsten Madsen, Chief Medical Officer and 4 others. "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. Contact Information Website www.syndesitherapeutics.com The VIVES Louvain Technology Fund (www.vivesfund.com) is a multi-sector technology fund which invests in the spin-offs of the Universit catholique de Louvain (UCL) and start-ups in Belgium and neighboring countries. The fund invests throughout Europe in start-up and early-stage companies with high growth potential focusing on technologies that provide transformational improvements in the biopharmaceutical, pharmaceutical, diagnostics and agricultural sectors. Syndesi Therapeutics - Crunchbase Company Profile & Funding This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Read more Press releases "I am delighted with the closing of this deal. Syndesi Therapeutics's Chief Executive Officer is Jonathan Savidge. Syndesi Therapeutics | CipherBio AbbVie makes neuro drug connection with $130M Syndesi Therapeutics Registration or use of this site constitutes acceptance of our Terms of Service and Privacy Policy. Novo Holdings A/S (formerly Novo A/S) is the Novo Nordisk Foundation's wholly owned holding company for Novo Nordisk A/S and Novozymes A/S.Novo Holdings A/S was established in 1999 and manages the Novo Nordisk Foundation's assets, which in 2021 was worth almost DKK 700 billion Danish Kroner (approximately US$93.73 billion) and is the largest charitable foundation in the world making Novo . GPRC5D-Targeted Therapy: Target Expression Profile, Safety & Efficacy of Drug Modalities, Pipeline Review, and Competitive Landscape Analysis, Report bundle: Claudin 6, Cadherin 17, ROR1 and GPRC5D-Targeted Therapies: Target Expression Profile, Safety & Efficacy of Drug Modalities, Pipeline Review, and Competitive Landscape Analysis, Targeted Protein Degradation by Proteasomal, Lysosomal & Autophagy Pathways 2022: an industry landscape analysis of stakeholders, technologies, pipeline, partnering and financing, Masked Antibodies & Cytokines As Prodrugs: a landscape analysis of stakeholders, technologies, pipelines, business and financing from an industry perspective, ROR1-Targeted Therapy: Target Expression Profile, Safety & Efficacy of Drug Modalities, Pipeline Review, and Competitive Landscape Analysis, PipelineReview.com is powered by La Merie Business Intelligence, For immediate assistance, please call us during business hours: Mon-Fri 10:00am - 05:00pm; GMT+01, La Merie Publishing - Ulrich Martin | Carrer Nria, 10, 3, 2a | 17500 Ripoll | Spain T +49-7934-6839 668 | F +49-3212-1267 572 | Email This email address is being protected from spambots. About Syndesi Therapeutics. Le ratio de marge brute ajuste tait de 84,7 % ; la marge d'exploitation du deuxime trimestre tait de . Anthos Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic . It is being evaluated in a phase 1b study to treat cognitive impairment associated with various neurodegenerative disorders such as . MT . 2007 -2022 UCB S.A., Belgium. AbbVie Acquires Syndesi Therapeutics, Strengthening - Yahoo! UCB is listed on Euronext Brussels (symbol: UCB). Syndesi Therapeutics SA, a clinical stage biotechnology company developing novel modulators of the synaptic vesicle protein SV2A for the treatment of cognitive impairment, provides an update on the clinical development of its lead molecule, SDI-118, and announces an extension of its series A financing. UCB is providing this information as of the date of this press release and expressly disclaims any duty to update any information contained in this press release, either to confirm the actual results or to report a change in its expectations. About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. In 2017, the Belgian pharmaceutical company established a partnership with an investor group that included Novo Holdings, Fountain Healthcare Partners, and Johnson & Johnson InnovationJJDC. With AbbVies acquisition of Syndesi, we aim to advance the research of a novel, first-in-class asset for the potential treatment of cognitive impairment associated with neuropsychiatric and neurodegenerative disorders.. There is no guarantee that new product candidates in the pipeline will progress to product approval or that new indications for existing products will be developed and approved. When it comes to contacting clinicians and patients, the hospital switchboard can be just as [], AbbVie, alzheimer's disease, Clinical Trials, deals, life sciences M&A, neuroscience, North Chicago, UCB. About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. The UK Life Sciences team advised Syndesi Therapeutics and its shareholders on Syndesi's acquisition by AbbVie (NYSE: ABBV). Tick the boxes of the newsletters you would like to receive. Regulating synaptic transmission represents a promising approach to treating Alzheimers Disease and other disorders with cognitive impairment. Syndesis molecule is currently in early-stage clinical development as a way to target nerve terminals to enhance synaptic efficiency. COPENHAGEN, Denmark, March 1, 2022 /PRNewswire/ -- Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics ('Syndesi'). About Syndesi Therapeutics . The company is the holding company in the Novo Group, comprising Novo Nordisk A/S, Novozymes A/S and NNIT A/S, and is responsible for managing the Foundations assets. Ferrous(II) glycine sulphate complex (Ferro Sanol), Plain language summaries of study results, Access to Patient-Level Clinical Study Data, Plain Language Summaries of research results, Registration and Results Reporting on Public Registries, Cimzia - Axial spondyloarthritis (axSpA), Privacy Policy for Healthcare Professionals, Syndesi Therapeutics to leverage UCBs expertise in neurology drug discovery to develop potential therapeutics in cognitive disorders with a first-in-class mechanism, Series A financing of 17 M from a syndicate of Belgian and international investors. AbbVie Acquires Syndesi Therapeutics, Strengthening Neuroscience All rights reserved. PATIENTS & FAMILIES. ABOUT HD; ABOUT ALS; NEWS. Therefore we make use of cookies. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. The Company's approach is aimed at treating Alzheimer's Disease and other disorders with cognitive impairment. Established in 2017, Syndesi focuses on developing new treatments that regulate synaptic activity to alleviate cognitive impairment symptoms. Bone Therapeutics is a bone cell therapy company specializing in addressing unmet medical needs in the field of orthopaedics and bone diseases. Synaptic dysfunction is believed to. Send. The lead molecule, SDI-118, is a small molecule currently in Phase 1b studies, which is being evaluated to target nerve terminals to enhance synaptic efficiency. This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. document.getElementById('cloak45869').innerHTML += '' + addy45869+'<\/a>'; We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. The mechanism is currently being evaluated for the potential treatment of cognitive impairment and other symptoms associated with a range of neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease and major depressive disorder. Stay up-to-date on the latest news and information from UCB, 2007 - 2022UCB S.A., Belgium. The funds (VIVES I - 15 million and VIVES II - 43 million) are managed by SOPARTEC, UCLs technology transfer company, member of the Louvain Technology Transfer Office. Macrophage Therapeutics, Inc. Syndesi Therapeutics is funded by 9 investors. OUR PIPELINE JOIN US TODAY V-Bio Ventures (www.v-bio.ventures) is an independent venture capital firm specialized in building and financing young, innovative life science companies. The anchor of AbbVies neuroscience portfolio is probably botox. Syndesi Therapeutics serves customers worldwide. Syndesi | VentureRadar AbbVie Acquires Syndesi Therapeutics - World Pharma Today About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment.

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